10 prisoners must sample the wine. Bonus points if you worked out a way to ensure than no more than 8 prisoners die.

Number all bottles using binary digits. Assign each prisoner to one of the binary flags. Prisoners must take a sip from each bottle where their binary flag is set.

Here is how you would find one poisoned bottle out of eight total bottles of wine.

Bottle 1 Bottle 2 Bottle 3 Bottle 4 Bottle 5 Bottle 6 Bottle 7 Bottle 8
Prisoner A X X X X
Prisoner B X X X X
Prisoner C X X X X
In the above example, if all prisoners die, bottle 8 is bad. If none die, bottle 1 is bad. If A & B dies, bottle 4 is bad.

With ten people there are 1024 unique combination so you could test up to 1024 bottles of wine.

Each of the ten prisoners will take a small sip from about 500 bottles. Each sip should take no longer than 30 seconds and should be a very small amount. Small sips not only leave more wine for guests. Small sips also avoid death by alcohol poisoning. As long as each prisoner is administered about a milliliter from each bottle, they will only consume the equivalent of about one bottle of wine each.

Each prisoner will have at least a fifty percent chance of living. There is only one binary combination where all prisoners must sip from the wine. If there are ten prisoners then there are ten more combination where all but one prisoner must sip from the wine. By avoiding these two types of combination you can ensure no more than 8 prisoners die.

One viewer felt that this solution was in flagrant contempt of restaurant etiquette. The emperor paid for this wine, so there should be no need to prove to the guests that wine is the same as the label. I am not even sure if ancient wine even came with labels affixed. However, it is true that after leaving the wine open for a day, that this medieval wine will taste more like vinegar than it ever did. C'est la vie.